The TRT dosage in my book is 100 to 200 mg of testosterone a week, with a blood level of 600 to 1,000 ng/dL as the target. It’s Level 4 on the Natty Spectrum, the hormone pathway of the Forever Protocol, and the one hormone I’ve run for most of the last thirteen years. TRT restores what age takes away, but it also shuts down your own production and your fertility. This page covers the dose, how to know you need it, the labs that keep it safe, and what the biggest heart trial found.
TRT means testosterone replacement therapy: you take testosterone because your body no longer makes enough. In the US, it’s usually an injection of testosterone cypionate or enanthate. Gels, creams and pellets also exist.
Testosterone drops 1 to 2 percent a year after 30, as I wrote in the opening chapters. For some men, the drop is small. For others, however, it brings low energy, low libido, lost muscle and a foggy head.
The catch is that your brain notices the outside testosterone and stops sending the signal to your testes. So once you start, your own production shuts down. That’s why the book treats TRT as a serious decision.
The book gives one range for replacement: 100 to 200 mg a week. It shows up as Level 4 of the Natty Spectrum in Chapter 6, in the hormone pathway of the Forever Protocol, and in my 80/20 Protocol “if testosterone is low.” The target on bloodwork is 600 to 1,000 ng/dL.
My own stack, as I describe it in Chapter 6, runs 300 mg a week on top of the Natural Plus foundation. That’s above the replacement range the book gives for everyone else. I’ve also said it plainly in the book: my natural testosterone and my fertility are suppressed, and if I started today, I’d start with the Natural Plus compounds first.
Before any TRT dosage, prove you need it. The two guidelines the book cites agree on the method [1][2]:
After all, one low test after a bad night isn’t a diagnosis. Below are the full TRT dosage table by goal, the hematocrit and estrogen rules, fertility, the heart data, the bloodwork schedule and who should skip it.
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This page documents Dr. Tony Huge’s research and self-experimentation. It is journalism and education, not medical advice, and it creates no doctor-patient relationship. Dr. Tony Huge holds a Juris Doctor; he is a lawyer, not a physician. Read the full Legal Disclaimer.